The established European market was highlighted by ShelterOffshore.com as a place where investors can enjoy year-round sunshine and a strong tourist trade.
However, lifestyle buyers were told that they too can find good quality houses away from the main holiday hotspots, allowing them to enjoy the good weather and natural environment in relative peace and quiet.
Alentejo was flagged up as one such location, as it has a "stunning coastline" and is free of "maddening crowds".
In addition, the region was praised for offering diverse landscapes, including lush plains, arid areas and national parks.
ShelterOffshore.com said: "Alentejo has such dramatic and diverse countryside that there is a town, village or rural location to suit everyone’s tastes."
The website added that property prices tend to be lower than in other regions such as the Algarve.
Portugal's popularity with second home buyers was recently highlighted by the Irish Independent, which said its lack of "unsightly overdevelopment" makes it preferable to many other established markets.