The new service has been described as a landmark for aviation in the United Arab Emirates, as it is the first time a premium carrier has departed from Dubai Airport's Executive Terminal.
Commenting on the new service, Katherine Gershon of Silverjet said: "The long-awaited London launch has officially arrived and Dubai couldn't be more excited."
She added that transport links to Dubai had reached a "whole new level", as passengers would be able to enjoy a variety of personalised and luxurious services.
Although the new service is being targeted towards a niche market, it still represents a further improvement to the accessibility of the region.
According to the Dubai Property Exhibition, the city attracted more than 250,000 new residents, making it the fastest growing conurbation in the world.